Cobalt chelates recognize two exposed vicinal histidines. This resin is used in many purifications because this cation provides very good selectivity.
Cobalt Rapid Run™ provides the advantages of the Cobalt cation with the high flow rates of the Rapid Run™ beads. It is specially designed for large scale His-tagged protein purifications.
Cobalt Rapid Run™
Bead Geometry & Size
Loading Capacity (μmol me2+/ml gel)
Exclusion Limit Da
Maximum Flow Rate at 15 cm Bed Height
≥ 1000 cm/h
Maximum Pressure at 15 cm bed Height≥ 300 kPa
Standard ~ 50-150 µm