Glutathione Agarose Resin

Glutathione Agarose Resin consists of glutathione covalently bound to agarose beads. This resin works well with small and large proteins tagged with GST in batch or column purifications (Low Flow).

REFERENCES:

  • Usategui-Martín, Ricardo et al. “A Mutation in P62 Protein (p. R321C), Associated to Paget’s Disease of Bone, Causes a Blockade of Autophagy and an Activation of NF-KB Pathway.” Bone 133 (2020): n. pag. Bone. 
  • Gloerich, Martijn et al. “Cell Division Orientation Is Coupled to Cell-Cell Adhesion by the E-Cadherin/LGN Complex.” Nature Communications 8 (2017): n. pag. Nature Communications. 
  • Cabrera, Margarita et al. “Chaperone-Facilitated Aggregation of Thermo-Sensitive Proteins Shields Them from Degradation during Heat Stress.” Cell Reports 30.7 (2020): 2430-2443.e4. Cell Reports.
  • Carabias, Arturo et al. "Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas." Sci. Signal. 13, eabb7075 (2020)
  • Product Name Glutathione Agarose Resin
  • Cat. No. 4B-GLU-X
  • Bead Geometry & Size Spherical ~50 - 150 µm
  • Crosslinked No
  • Agarose % 4 %
  • Antimicrobial Agent 20 % ethanol
  • Static Binding Capacity ≥ 8 mg recombinant GST / ml gel
  • Storage Temperature 4-8 C°
  • Ligand Glutathione, linked via sulphur atom
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