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Revolutionize rabbit reproduction with Agarose Bead Technology. Our high-density nickel columns ensure pure and stable rrβ-NGF, enhancing sperm motility and ovulation induction
Advances in molecular biology and biochemistry have revolutionized the field of reproductive biotechnology. This study published in PLOS ONE, "Recombinant rabbit beta nerve growth factor production and its biological effects on sperm and ovulation in rabbits," highlights the potential of recombinant rabbit β-NGF (rrβ-NGF) in improving rabbit reproduction.
This is where Agarose Bead Technology's products come into play, offering innovative solutions for the challenges faced in this field.
Agarose Bead Technology specializes in the purification and handling of delicate biological compounds like rrβ-NGF.
"AGAROSE BEAD TECHNOLOGY'S IMAC PRODUCTS INCREASE THE PURITY AND YIELD OF rrβ-NGF"
Our high-density nickel columns provide a gentle yet effective medium for purifying rrβ-NGF produced in CHO cells, as described in the study.
By using our technology, researchers can ensure higher purity and stability of rrβ-NGF, which is critical for its biological effectiveness. The study demonstrated that rrβ-NGF improved sperm motility without affecting its viability (Figure 1), and the the ovulation-inducing effect of rrβ-NGF when added to seminal doses in female rabbits.
Attending to the results of this study, Agarose Bead Technology's IMAC products increase the purity and yield of rrβ-NGF.
Figure 1. Sperm viability (A) and motility parameters assessed by CASA (B-I) at 0, 1 and 2 h post addition of different doses of rrβ-NGF (0, 20, 100 ng/mL, 1 μg/mL) to fresh rabbit semen samples. Concentrations of rrβ-NGF (0, 20, 100 ng/mL, 1 μg/mL) are represented in graded blue. Statistical differences among different concentrations at each time point are indicated by lines (p<0.05) except for VAP, whose line indicates differences between times. NS: non-significant differences. Data are represented as means ± SEM.
Our commitment to advancing research and development in this field is firm, as we continue to offer innovative solutions that meet the evolving needs of scientists and researchers worldwide.
1. Sanchez-Rodriguez A, Abad P, Arias- Alvarez M, Rebollar PG, Bautista JM, Lorenzo PL, et al. (2019). Recombinant rabbit beta nerve growth factor production and its biological effects on sperm and ovulation in rabbits. PLoS ONE 14(7): e0219780. https://doi.org/10.1371/journal.pone.0219780