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Affinity Chromatography
Nickel Rapid Run™
Nickel chelate resins recognize two exposed histidines for an appreciable retention of a protein and it is recommended in the majority of the cases. This resin works well with relatively easy to separate His-tagged proteins.
Nickel Rapid Run™ provides the advantages of the Nickel cation with the high flow rates of the Rapid Run™ beads. It is specially designed for large scale His-tagged protein purifications.